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Assistive intervention

The general reference term of i-PROGNOSIS interventions that do not belong to the PGS. Assistive interventions are the targeted nocturnal intervention, the voice enhancement intervention and the gait rhythmic guidance intervention.


Behavioural model

A behavioural model that will be produced based on interventions performance and engagement data from a particular interventions user and it will relate to the user’s inclination towards self-health management.

Body/gesture recognition

The algorithmic recogntion of a person’s posture and gestures based on data provided by the Kinect device.


Slowness of movement


Cloud server

An server of the i-PROGNOSIS Microsoft Azzure Cloud-based data management infrastructure (server farm).

COMT inhibitors

A Catechol-O-Methyl Transferase inhibitor is an enzyme which inhibits the action of catechol-O-methyl transferase. This enzyme is involved in degrading neurotransmitters.


DaT Scan

A contrast agent to be used with single-photon emission computed tomography (SPECT) for detecting dopamine transporters (DaT) in suspected parkinsonian syndromes

Detection application

The i-PROGNOSIS mobile application (for smartphone) that includes the UI and all the services needed for the first and second stage of the i-PROGNOSIS Parkinson’s disease detection.

Dietary game

An electronic game involving a set of gamified scenarios, part of the personalised game suite, targeting the improvement of dietary habits.


Abnormality or impairment of voluntary movement



An electronic game involving a set of gamified scenarios, part of the personalised game suite, targeting the improvement of facial emotional expressions.


An electronic game involving a set of gamified scenarios, part of the personalised game suite, targeting the improvement of facial emotional expressions.



18-flurodopa PET scan

Fatigue Severity Scale

A 9-item scale which measures the severity of fatigue and its effect on a person’s activities and lifestyle in patients with a variety of disorders.


Gait rhythmic guidance intervention (GRGI)

An assistive intervention that will provide sound/vibration-based cues for assisting gait or for overcoming freezing episodes when the user walks.

Game scenario

The context and the ensemble of actions that form a stage of each game in the personalised game suite.


The General Data Protection Regulation (GDPR) (EU) 2016/679 is a regulation of the EU law on data protection and privacy for all individuals within the European Union and the European Economic Area.

Google Wear OS

A version of the Android operating system (OS) designed for smartwatches and other wearables.


Handwriting game

An electronic game involving a set of gamified scenarios, part of the personalised game suite, targeting the improvement of handwriting.

Hoehn and Yahr scale

The Hoeh and Yahr scale is a commonly used system for describing how Parkinson’s disease symptoms progress in stages.

Hospital Anxiety and Depression Scale (HADS)

A test commonly used by physicians to determine the levels of anxiety and depression that a patient is experiencing.



An activity of the i-PROGNOSIS system developed to sustain the quality of life of the user.




A commercial device that has the required sensors for the user to interact with the games by gestures and body movements. The Kinect® is developed by Microsoft Corporation, Redmond, WA.




A plate scale that is placed under the plate of the meal that the userconsumes and that collects and transmits food intake data to the smartphone. The Mandometer® is developed by Mando Group AB, Huddinge, Sweden.

MAO-B inhibitors

Monoamine oxidase inhibitors (MAOIs), were developed as initial antidepressants


A motion sensor device equiped with RGB camera and depth sensor for tracking motion. The MentorAge device is equipped with Android OS and is developed Nively, Nice, France.

Montreal Congnitive Assessment (MoCA)

The Montreal Cognitive Assessment (MoCA) is a widely used screening assessment for detecting cognitive impairment.


Non-motor Symptoms (NMS) Scale

A physician-based scale for assessing non-motor symptoms in Parkinson’s disease.

Non-motor Symptoms Questionnaire (NMSQ)

The non-motor symptoms questionnaire (NMSQ) is a self-administered screening tool comprising 30 items of non-motor symptoms and it is used to identify presence of such symotms for further investigation.



Parkinson’s Disease Questionnaire (PDQ)

This questionnaire assesses how often people affected by Parkinson’s experience difficulties across 8 dimensions of daily living. There is a long (39 items) and short version (8 items).

Parkinson’s Disease Sleep Scale (PDSS)

Parkinson’s disease sleep scale (PDSS) is a scale that assesses the profile of nocturnal disturbances in Parkinson’s disease (PD) patients.

Perfomance metric

The metric that will quantitatively (score) or qualitatively (achievement) indicate how the user performed during a personalised game suite game scenario.

Personalisation service

A service of a personalised game suite game that adapts the game play based on the user’s previous performance(s).

Personalised game suite

The collection of the i-PROGNOSIS gamified interventions (Exergames, Dietary game, Handwriting game, Voice game, Emogame) with personalised adaptation services for the user.



Quality-adjusted life year


REM sleep Behaviour Disorder Screening Questionnaire (RBDSQ)

A test to facilitate the diagnosis and recruitment of patients with REM Sleep Behavior Disorder.


Stiffness or inflexibility of muscles


Schedule for the Evaluation of the Individual Quality of Life – Questionnaire (SEIQoL-Q)

A test for measuring individual quality of life in patients.

Short Physical Performance Battery (SPPB)

The Short Physical Performance Battery (SPPB) is a well-established tool to assess lower extremity physical performance status.

Smart belt

A belt worn around the abdomen that bears microphones and other hardware that captures and transmits bowel sounds to the smartphone.

Smart TV remote

A TV remote controller that besides serving as a regular and universal TV remote controller bears electrocardiogram (ECG) sensors and other hardware that captures and transmits ECG data to the smartphone.


A smart (with advanced features and sensors to capture physical activity and physiological data) watch that connects to her/his smartphone.

Starkstein Apathy Scale (14-item)

The Starkstein Apathy Scale is a scale consisting of 14 items that is used to screen for and measure the severity of apathetic symptoms in Parkinson’s disease.


Targeted nocturnal intervention (TNI)

An assistive intervention targeting the sleep stage reinstatement of the user after a sleep disturbance episode.

Ten-meter walk test

Ten-meter walk test is a performance measure used to assess walking speed in metres per second over a short distance. It can be employed to determine functional mobility, gait, and vestibular function.

Time Up and Go (TUG) test

A test to determine fall risk and measure the progress of balance, sit to stand, and walking.

Tinetti mobility test

A test to assess gait and balance in older adults.


Unified Parkinson’s Disease Rating Scale

The Unified Parkinson’s Disease Rating Scale (UPDRS) is used to follow the longitudinal course of Parkinson’s disease. Part III of this scale is widely used by movement disorder specialists to evaluate motor symptoms of the disease.


Virtual tutor

A virtual avatar, representing a tutor, that is part of the interventions platform and it guides and motivates users before, during and after their engagement with the games using natural language (oral or text).

Voice enhancement intervention (VEI)

An assistive intervention targeting the improvement of voice quality in recorded voice messages that the user can share to third-party compatible mobile apps, e.g. WhatsApp.

Voice game

An electronic game involving a set of gamified scenarios, part of the personalised game suite, targeting the improvement of oral communication.

Voice Handicap Index (VHI)

The Voice Handicap Index (VHI) measures the influence of voice problems on a patient’s quality of life.